NFL predictions: Week 10 odds & expert betting tips

Week nine saw another set of upsets as the Vikings, Panthers and Steelers took care of business beating the Lions, Packers and Colts respectively. The Bengals continued their poor run of form losing 47-42 against the Bears and the Bills beat the Chiefs in the main game of the week.

Fortunately, we had some decent winners again, especially in the later games as we landed a 23/10 bet, a 19/10 and EVS money touchdown scorers. 

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Now we look ahead to week 10 where we have plenty of exciting matchups and hopefully even more winners.

Baltimore Ravens @ Minnesota Vikings betting tips

When: Sunday 18:00pm UK time

Where to watch: Sky Sports NFL

The Ravens are on the move now and are starting to turn around their poor start. After week six they were 1-5 but they have now got a lot of their starters back and have just won their last two games.

Lamar Jackson being healthy again is huge for Baltimore and that was seen last week against the Dolphins. The former MVP winner had four passing touchdowns against Miami and that is something the Ravens have been missing.

Also, the defence has looked much better over the last two weeks only giving up 22 points. Here they take on a Minnesota Vikings team that also managed to get a win last week.

The Vikings had JJ McCarthy back from injury and he had a solid game against the Detroit Lions. His performances at the beginning of the season were not great and although he was better last week, he still wasn’t amazing.

The Vikings defence has looked solid all year, and it will need to be in this game. It’s hard to have confidence in the Vikings when McCarthy hasn’t really played much. The Ravens however look like they are getting back to their best.

FIRST.com’s top tips

Pick 1: Ravens -3.5 @ 5/6 (Ladbrokes)

Pick 2: Justin Jefferson anytime TD @ 13/10 (Betway)

Pick 3: Mark Andrews anytime TD @ 7/4 (10Bet)

New England Patriots @ Tampa Bay Buccaneers betting tips

When: Sunday 18:00pm UK time

Where to watch: Sky Sports NFL

The Patriots just can’t stop winning now. Even when they don’t play great, they are still getting the result. Last week saw them win their sixth game in a row and now they have a 7-2 record. 

Drake Maye had his worst game in quite a few weeks against the Falcons last Sunday, but they still won. 

The defence is flying now and is ranked ninth in the league. They don’t have a star wide receiver, but it feels like they don’t need one given how everyone is playing for each other.

This game will be the Patriots biggest test for a while as they go up against a solid Buccaneers team. They are top of the NFC South and have a 6-2 record. Also, they are coming off a bye so they should be a bit fresher than their opposition.

Mike Evans and Chris Godwin are still out injured so Baker Mayfield will have to rely on rookie wide receiver Emeka Egbuka again. The former Ohio State star has been electric this season and could have another good game here. 

This will be an interesting game and a good test for the Patriots to see how good they really are.

FIRST.com’s top tips

Pick 1: Buccaneers -2.5 @ 10/11 (Ladbrokes)

Pick 2: Emeka Egbuka anytime TD @ 6/5 (10Bet)

Pick 3: Hunter Henry anytime TD @ 23/10 (William Hill)

Detroit Lions @ Washington Commanders betting tips

When: Sunday 21:25pm UK time

Where to watch: 5Action

The Lions have had a bumpy first half of the season compared to previous years. They are currently second in the NFC North and have a 5-3 record. Losing both offensive and defensive coordinators in the offseason was always going to cause an issue.

However, they still look like a good team who can compete at the top. They lost at home to the Vikings last week which was a surprise but that feels more like a blip than a big problem. 

Here they take on a Commanders team that saw their chances of playoff football disappear last week. A big loss against the Seahawks saw them go to a 3-6 record. However, the bigger loss was the injury to star quarterback Jayden Daniels.

Daniels dislocated his elbow late in the game and is now out for the season. Also, star wide receiver Terry McLaurin has missed most of this season with a quad injury. 

Marcus Mariota will be the starter for the rest of the season now and the quarterback can win games. However, against the Lions might be a step too far.

FIRST.com’s top tips

Pick 1: Over 48.5 @ 20/23 (Betway)

Pick 2: Sam LaPorta anytime TD @ 13/10 (William Hill)

Pick 3: Zack Ertz anytime TD @ 3/1 (William Hill)

LA Rams @ San Francisco 49ers betting tips

When: Sunday 21:25pm UK time

Where to watch: Sky Sports NFL

The Rams have looked good this year and are second in their division with a 6-2 record. Quarterback Matthew Stafford has been playing like the MVP passing for 2,147 yards, 21 touchdowns and only two interceptions.

He has got his star wide receiver back in Puka Nacua after a slight injury and veteran receiver Davante Adams has been great this season. The defence is also ranked in the top 10 over the first nine weeks and after losing to the 49ers earlier in the season they will be out for revenge.

The 49ers have done well to have a 6-3 record this season but are only third in a tough division. They had the easiest schedule when the season started but have been decimated by injuries again.

It feels like the injuries are starting to take their toll now and they just can’t compete against the better sides. They got a solid win last week against the Giants but lost to a good Texans defence the week before. It’s hard to see them stopping this Rams juggernaut with all these players missing.

FIRST.com’s top tips

Pick 1: Rams -3 @ 13/20 (Ladbrokes)

Pick 2: Davante Adams anytime TD @ 9/10 (10Bet)

Pick 3: George Kittle anytime TD @ 7/4 (William Hill)

Pittsburgh Steelers @ LA Chargers betting tips

When: Monday 01:20am UK time

Where to watch: Sky Sports NFL

The Pittsburgh Steelers are top of their division and have a 5-3 record. They have had a bit of a bumpy ride over the last few weeks but got a good win against the Colts last week. 

Aaron Rodgers has looked like his old self in Pittsburgh, and it wouldn’t be shocking if he came back for another year. The defence is ranked 30th in the league and needs to improve if they have any chance of winning this division.

Here they take on a Chargers team that have looked good this season, but injuries are a concern. They lost standout left tackle Joe Alt last week from the offensive line and will be a huge miss.

They have big injuries in other areas as well but fortunately they have Justin Herbert firing on all cylinders. In the last four weeks he has thrown ten touchdowns and should have a good game against the Steelers struggling defence.

FIRST.com’s top tips

Pick 1: Chargers -3.5 @ 21/20 (Ladbrokes)

Pick 2: Oronde Gadsden anytime TD @ 19/10 (10Bet)

Pick 3: Calvin Austin anytime TD @7/2 (10Bet)

Philadelphia Eagles @ Green Bay Packers betting tips

When: Tuesday 01:15am UK time

Where to watch: Sky Sports NFL

The defending Super Bowl champions are looking good again this season and are top of the NFC East with a 6-2 record. They did have a small blip in the middle of the first nine weeks when they lost to the Broncos and Giants.

However, they seem to have gotten over that with wins against the Vikings and Giants. The defence has not been as good this year, and they have traded for some extra help. This will be a good tester for the Eagles.

The Packers have been a strange side this year, but they can beat anyone on their day. They have a 5-2-1 record, but their two losses have been against the Browns and the Panthers. Two teams that the Packers should be beating easily.

The loss to the Panthers last week was a big blow but the loss of Tucker Kraft to injury was bigger. Kraft has been a rock for this offence and losing him is going to make the offence change if they want to win games. This game should be fascinating. 

FIRST.com’s top tips

Pick 1: Eagles Moneyline @ 11/10 (Priced Up)

Pick 2: DeVonta Smith anytime TD @ 9/4 (Betway)

Pick 3: Luke Musgrave anytime TD @ 3/1 (10Bet)

Quickfire predictions – week 10 tips

Falcons @ Colts

Pick 1: Over 48.5 @ 10/11 (10Bet)

Pick 2: Michael Pittman anytime TD @ 13/8 (William Hill)

Bills @ Dolphins

Pick 1: Over 50.5 @ EVS (Priced Up)

Pick 2: Dalton Kincaid anytime TD @ 11/4 (10Bet)

Jaguars @ Texans

Pick 1: Jaguars -1.5 @ 10/11 (Betway)

Pick 2: Jakobi Meyers anytime TD @ 5/2 (William Hill)

Giants @ Bears

Pick 1: Over 46.5 @ 10/11 (Priced Up)

Pick 2: Jaxson Dart anytime TD @ 2/1 (10Bet)

Browns @ Jets

Pick 1: Browns -1.5 @ 20/23 (Betway)

Pick 2: Breece Hall anytime TD @ 10/11 (Betway)

Saints @ Panthers

Pick 1: Over 38.5 @ 4/5 (Priced Up)

Pick 2: Juwan Johnson anytime TD @ 9/2 (Betway)

Cardinals @ Seahawks

Pick 1: Over 44.5 @ 10/11 (Ladbrokes)

Pick 2: Marvin Harrison anytime TD @ 33/20 (Betway)

Previous Games/Odds

30/10/2025

Minnesota Vikings @ Detroit Lions betting tips

When: Sunday 2 November, 18:00pm UK time

Where to watch: Sky Sports NFL

The Vikings are now 3-4 and are struggling to get wins. Their biggest problem is a lack of talent at the quarterback position. JJ McCarthy struggled in the Vikings first two games before getting injured. Then Carson Wentz came in, and he didn’t improve the team.

Now Wentz has had season ending surgery and it looks like an injured McCarthy could be rushed back for this game. The defence has looked solid but it’s hard when you are on the field too much.

Here they are going up against a Lions team that are flying again. At 5-2 they are competing with the Packers for the NFC North title this year. Jared Goff has been predictably solid, and all their offensive weapons are doing well.

Their defence is still doing well, and they have just re-signed star edge rusher Aidan Hutchinson to a new four-year deal. It’s hard to see the Vikings competing much in this one and with the Lions being at home a win should be comfortable for them.

FIRST.com’s top tips – Vikings @ Lions

Pick 1: Lions -8.5 @ 20/21 (PricedUp)

Pick 2: Over 48.5 @ 19/20 (Ladbrokes)

Pick 3: Amon-Ra St Brown anytime TD scorer @ 21/20 (Betway)

Indianapolis Colts @ Pittsburgh Steelers betting tips

When: Sunday 2 November, 18:00pm UK time

Where to watch: Channel 5

I don’t think anyone saw this coming from the Indianapolis Colts this season. At 7-1 they are leading the whole of the AFC conference. Daniel Jones has been a revelation for this Colts team and star running back Jonathan Taylor is providing an MVP calibre season.

The offensive line doesn’t get the plaudits that it deserves and is one of the main reasons for this great start. Defensively they are not the best and you can score against them. 

However, they look like they can outscore anyone with Michael Pittman and rookie Tyler Warren having great seasons as well.

In this game the Colts are travelling to Pittsburgh to take on a Steelers team that are very different from previous years. Normally their defence is good, and they have a run heavy offence. 

This year it's all about Aaron Rodgers and the passing game and the defence has fallen apart. 

The front seven are still good with TJ Watt leading the line. However, their secondary is struggling, and they will probably be here again. Expect an exciting game where the Colts are likely to outscore the Steelers.

FIRST.com’s top tips - Colts @ Steelers

Pick 1: Colts -3 @ 10/11 (10Bet)

Pick 2: Michael Pittman over 4.5 total receptions @ 5/8 (Betway)

Pick 3: Michael Pittman anytime TD scorer @ 7/4 (10Bet)

Denver Broncos @ Houston Texans betting tips

When: Sunday 2 November, 18:00pm UK time

Where to watch: Sky Sports NFL

The Broncos are flying this season with a 6-2 record. They are currently top of the AFC West which is no mean feat considering they are against the Chiefs and Chargers. Their defence has easily been a top ten one this season and it makes a huge difference.

Bo Nix has been up and down this season, but he doesn’t need to be amazing all the time for the Broncos to get wins. He has had 15 touchdowns and five interceptions this season, but his pass completion percentage needs to be better.

Here they are going up against a quality defence in the Texans who could slow the Broncos down. They only have a 3-4 record, but they are still a capable team. The defence is considered one of the best in the league and that will mean they will always be in games.

The offence is the reason they have been struggling this year. CJ Stroud still doesn’t look like the quarterback we saw in his rookie year. They played better last week against the 49ers, but they had loads of injuries. This will be a tight game with two great defences going up against each other.

FIRST.com’s top tips - Broncos @ Texans

Pick 1: Broncos Moneyline @ 21/20 (Ladbrokes)

Pick 2: Nico Collins anytime TD scorer @ 6/4 (William Hill)

Pick 3: Bo Nix anytime TD scorer @ 3/1 (Betway)

Chicago Bears @ Cincinnati Bengals betting tips

When: Sunday 2 November, 18:00pm UK time

Where to watch: Sky Sports NFL

The Bears have had a solid start to the season. They have a 4-3 record and are sitting third in the NFC North. There was lots of hype in the offseason and although they are not winning the division they are doing well.

This season should be about new head coach Ben Johnson developing second year quarterback Caleb Williams. The rest of the team is looking good, but Williams still needs work as he only has a 61.9% pass completion rate.

This week the Bears are travelling to the Bengals and are going up against a poor defence. Scoring on the Bengals should not be a problem as they are ranked 32nd in the league when it comes to how many yards they give up. 

Their defence might be awful, but the offence is back since they traded for veteran quarterback Joe Flacco. Out of the three games that Flacco has been quarterback, they have lost two of them. However, they are much more competitive with him and can win games. This should be an exciting matchup.

FIRST.com’s top tips – Bears @ Bengals

Pick 1: Over 51.5 points @ 20/21 (PricedUp)

Pick 2: Chase Brown anytime TD scorer @ 21/20 (Betway)

Pick 3: Rome Odunze anytime TD scorer @ 23/20 (Betway)

Kansas City Chiefs @ Buffalo Bills betting tips

When: Sunday 2 November, 21:25pm UK time

Where to watch: 5Action

This is probably the most anticipated game of the week as two big foes go up against each other once again. The Kansas City Chiefs haven’t had the best season but are getting back on course now. Wins against the Raiders and Commanders have got them to 5-3.

Patrick Mahomes has been the star of the show once again with 17 touchdown passes and only four interceptions. He has also rushed for four more touchdowns as well. They have now got Rashee Rice back and Xavier Worthy which is helping the offence a lot.

Going up against the Bills is a common thing for Chiefs fans now. They normally end up in the AFC Championship game most years against each other. This year the Bills have not got the AFC East all their own way. The Patriots are ahead of them, and the Bills sit second with a 4-3 record.

The Bills defence have struggled to stop the run this season and it is unlikely that will change anytime soon. They need Josh Allen and the offence to keep going if they want to get back to their best. This should be a tight game once again.

FIRST.com’s top tips – Chiefs @ Bears

Pick 1: Bills +2 @ 10/11 (10Bet)

Pick 2: Patrick Mahomes anytime TD scorer @ 11/4 (10Bet)

Pick 3: Dalton Kincaid anytime TD scorer @ 5/2 (10Bet)

Seattle Seahawks @ Washington Commanders betting tips

When: Monday 3 November, 01:20am UK time

Where to watch: Sky Sports NFL

The Seattle Seahawks have had a good start to the season and could contend for the NFC West title. They have a 5-2 record and are quietly going about their business. Sam Darnold has come in as quarterback and looked exactly like the guy who was with the Vikings last year.

With him and Jaxson Smith-Njigba the offence has always got a chance of competing. It's not just the offence that is playing well though. The defence is currently ranked 10th and they have a good special teams as well.

Here they face a Washington Commanders side that needs to start winning quickly. They have a 3-5 record, and it feels like they are struggling to get back to how they were last year. Jayden Daniels has suffered with a couple of small injuries and that has caused the offence to struggle. He should be back for this game though.

Terry McLaurin has already been ruled out of this game, and the defence just isn’t the same as last season. This is going to be tough for them to win this game but its almost a must win one for the Commanders. 

FIRST.com’s top tips – Seahawks @ Commanders

Pick 1: Seahawks -2.5 @ 3/4 (PricedUp)

Pick 2: Over 48.5 @ EVS (PricedUp)

Pick 3: Zack Ertz anytime TD scorer @ 23/10 (William Hill)

Quickfire predictions – week nine tips

Panthers @ Packers 

Pick 1: Over 43.5 @ 17/20 (PricedUp)

Pick 2: Tucker Kraft anytime TD scorer @ 5/4 (10Bet)

Falcons @ Patriots

Pick 1: Under 46.5 @ 4/5 (Ladbrokes)

Pick 2: Kayshon Boutte anytime TD scorer @ 11/5 (Betway)

49ers @ Giants

Pick 1: 49ers -3.0 @ 21/20 (Ladbrokes)

Pick 2: George Kittle anytime TD scorer @ 27/20 (Betway)

Chargers @ Titans

Pick 1: Chargers -8.5 @ 10/11 (Betway)

Pick 2: Oronde Gadsden anytime TD scorer @ 6/4 (Betway)

Jaguars @ Raiders

Pick 1: Jaguars -2.5 @ 5/6 (PricedUp)

Pick 2: Brock Bowers anytime TD scorer @ 19/10 (10Bet)

Saints @ Rams

Pick 1: Over 43.5 @ 20/23 (Betway)

Pick 2: Davante Adams anytime TD scorer @ EVS (Betway)

Cardinals @ Cowboys

Pick 1: Over 52.5 @ 4/5 (Ladbrokes)

Pick 2: Jake Ferguson anytime TD scorer @ 21/10 (William Hill)

25/10/2025

New York Giants @ Philadelphia Eagles betting tips

When: Sunday 17:00pm UK time

Where to watch: Channel 5

The Giants had a tough start to the season going 0-3. At that point they benched starting quarterback Russell Wilson and moved on to rookie Jaxson Dart. The former Ole Miss star has improved the offence immeasurably and they have been 2-2 with him playing.

With the offence being better it has given the defence more time off the field. This has improved them as well and now the Giants are a much more competitive team. Victories against the Eagles and Chargers over the last four weeks have shown that they can be good again.

The Eagles had a great start to the season going 4-0 but then found things harder against the Broncos and Giants. Fortunately for Eagles fans they got back to winning ways with a victory against the Vikings. 

It’s not been the same this year as it was during their Super Bowl run last season. However, they are still a tough team to beat and will be a threat once the playoffs come around. Expect the Eagles to want revenge after losing to the Giants just two weeks ago.

FIRST.com’s top tips – Giants @ Eagles

Pick 1: New York Giants +7.5 @ 20/23 (Betway)

Pick 2: Over 42.5 @ 8/11 (Ladbrokes)

Pick 3: Jaxson Dart anytime TD @ 12/5 (Betway)

Chicago Bears @ Baltimore Ravens betting tips

When: Sunday 17:00pm UK time

Where to watch: Sky Sports NFL

The Chicago Bears fell to an 0-2 start but have turned things around quickly and now have a 4-2 record. It’s been a great start for new head coach Ben Johnson, and it feels like his identity is starting to show in this team now.

Caleb Williams still needs to improve and that should happen in time. They have got lots of offensive weapons and a defence that is currently ranked 11th in the league. It still feels that this is a transition year, but they are a team that can cause a few upsets.

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Here the Bears are going up against a Baltimore Ravens team that has had a rough start to the season. Their defence has been awful and sits bottom of the league, although, the caveat being, they have been decimated with injuries.

The offence has struggled as well, largely due to Lamar Jackson being out injured the last two games. 

He should be back for this game which should make a difference, but the defence is still a huge problem. At 1-5 the Ravens need to win now otherwise their season could be done.

FIRST.com’s top tips – Bears @ Ravens

Pick 1: Chicago Bears + 6.5 @ 10/11 (PricedUp)

Pick 2: Over 49.5 @ 19/20 (Coral)

Pick 3: Rome Odunze anytime TD scorer @ 6/4 (William Hill)

San Francisco 49ers @ Houston Texans betting tips

When: Sunday 17:00pm UK time

Where to watch: Sky Sports NFL

The 49ers are another team that have been hit with the injury bug. Brock Purdy, George Kittle, Mac Jones, Ricky Pearsall, Brandon Aiyuk, Nick Bosa and Fred Warner have all been injured at one point this season. It’s crazy how they have managed to stay so competitive.

They currently have a 6-1 record and have only lost away to the Jaguars. Christian McCaffery has looked back to his usual self after being injured last season. 

He has amassed nearly a thousand rushing and receiving yards and got six touchdowns. If he can keep going, then the 49ers will always have a chance.

They are travelling to Houston to play a Texans team that just hasn’t really got going all season. They are 2-4 and sit third in the AFC South. They have only managed to beat the Titans and the Ravens. Two teams who sit in the bottom third of the league table when it comes to defence.

The Texan’s defence has been decent this season and has kept them in games, but the offence has struggled. CJ Stroud doesn’t look like the player we saw in his rookie year and that is largely due to a poor offensive line. This should be a close contest.

FIRST.com’s top tips – 49ers @ Texans

Pick 1: San Francisco 49ers +1.5 @ 20/21 (PricedUp)

Pick 2: Under 43.5 @ 7/10 (Coral)

Pick 3: George Kittle anytime TD scorer @ 19/10 (William Hill)

Dallas Cowboys @ Denver Broncos betting tips

When: Sunday 20:25 UK time

Where to watch: 5Action

The Dallas Cowboys are one of the most entertaining teams to watch this season. They have got one of the worst defences in the league but one of the best offences. Dak Prescott has been great this season passing for 1,881 yards, 16 touchdowns and three interceptions.

Not only has Dak been great but Javonte Williams has been great at running back. George Pickens and CeeDee Lamb have also been superb when fit. Their defence isn’t going to get any better anytime soon, so they must keep attacking to win games.

Here they are going up against the leaders of the AFC West. The Broncos have not looked fantastic but have a 5-2 record. They have won their last four games in a row including an amazing comeback last Sunday against the Giants.

To be 19-0 down with 14 minutes to go and comeback and win 33-31 is impressive and shows fight. This game could be one of the best of the week with both offences capable of high scoring. 

FIRST.com’s top tips – Cowboys @ Broncos

Pick 1: Denver Broncos -1.5 @ 4/6 (PricedUp)

Pick 2: Over 47.5 @ 13/20 (Ladbrokes)

Pick 3: Jake Ferguson anytime TD scorer @ 17/10 (William Hill)

Green Bay Packers @ Pittsburgh Steelers betting tips

When: Monday 00:20am UK time

Where to watch: Sky Sports NFL

After the first two weeks it felt like the Packers were the Super Bowl elect. Wins against the Lions and Commanders sent the media into a frenzy. However, a loss to the Browns and a tie against the Cowboys saw that hype crash. 

Now they are 4-1-1 but they haven’t looked amazing getting there. All four wins have ended with just 27 points in each game, and they are relying on their defence to get over the line. This isn’t a bad thing, it's complementary football. 

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Here they are taking on a Pittsburgh Steelers team that also have won plenty of games but did not look amazing. They currently sit with a record of 4-2 but they could have been better and surprisingly their defence is letting them down.

Aaron Rodgers has had a good season so far and that looks likely to continue. He is going up against a good Packers defence here though and his offensive line needs to be great for the Steelers to win. This one should be a close one.

FIRST.com’s top tips – Packers @ Steelers

Pick 1: Pittsburgh Steelers + 3.5 @ 10/13 (Betway)

Pick 2: Under 45.5 @ 20/23 (Betway)

Pick 3: Tucker Kraft anytime TD scorer @ 8/5 (Betway)

Washington Commanders @ Kansas City Chiefs betting tips

When: Tuesday 00:15am UK time

Where to watch: Sky Sports NFL

It hasn’t felt the same for the Commanders this season compared to last. Jayden Daniels has missed some time with injuries and star wide receiver Terry McLaurin has missed all the season so far. 

Defensively they are not as strong as they were last season as well. They have a 3-4 record and have got a tough schedule coming up over the next three weeks. Jayden Daniels is likely to miss this game and it’s hard to see them winning in Kansas.

The Chiefs had a slow start to the season, but things have heated up for them now. They are only third in their division with a 4-3 record, but they are getting stronger as the season goes on.

A 31-0 win against division rivals, the Raiders, is a huge statement both offensively and defensively. Rashee Rice is back from his suspension and got two touchdowns last week. It’s all positive in Kansas now and another win is expected in this game.

FIRST.com’s top tips – Commanders @ Chiefs

Pick 1: Kansas City Chiefs -9.5 @ 8/13 (Ladbrokes)

Pick 2: Under 48.5 @ 5/6 (Ladbrokes)

Pick 3: Rashee Rice anytime TD scorer @ 5/4 (William Hill)

Quickfire predictions – week eight tips

Bills @ Panthers

Pick 1: Over 46.5 @ EVS (PricedUp)

Pick 2: Khalil Shakir anytime TD @ 37/20 (Betway)

Browns @ Patriots

Pick 1: Over 40.5 @ 10/11 (Coral)

Pick 2: Kayshon Boutte anytime TD scorer @ 13/5 (Betway)

Dolphins @ Falcons

Pick 1: Over 43.5 @ 4/5 (PricedUp)

Pick 2: Kyle Pitts anytime TD scorer @ 2/1 (Betway)

Jets @ Bengals

Pick 1: Bengals -5.5 @5/6 (PricedUp)

Pick 2: Noah Fant anytime TD scorer @ 16/5 (Betway)

Buccaneers @ Saints

Pick 1: Over 47.5 @ EVS (Ladbrokes)

Pick 2: Sterling Shepard anytime TD scorer @ 12/5 (Betway)

Titans @ Colts

Pick 1: Michael Pittman over 4.5 Total receptions @ 5/7 (Betway)

Pick 2: Tyler Warren anytime TD scorer @ 11/10 (William Hill)

17/10/2025

LA Rams @ Jacksonville Jaguars betting tips

When: 14:30pm UK time

Where to watch: Channel 5

It’s been a good season so far for the Jacksonville Jaguars as they currently sit with a 4-2 record. They have had some impressive wins against the Kansas City Chiefs and the San Francisco 49ers. However, last Sunday they lost to the Seattle Seahawks in a tight low-scoring affair.

Nonetheless the massive positive for the Jaguars is that star wide receiver Brian Thomas seems to have found his spark again. 

Thomas had a slow start to this season not hitting over 55 yards in any of the first four games. 

But the last two weeks have shown he’s returning to his best, scoring his first touchdown last time out against the Seahawks.

The LA Rams are also coming into this game with a 4-2 record. They have only lost to the Philadelphia Eagles and 49ers this season and will be a tough nut to crack. The big concern for them currently is the fitness of Puka Nacua. 

The wide receiver has been great for them this season but missed parts of last week's win against the Baltimore Ravens due to an injury. With their bye in week eight it's likely he will miss this game and rest up for the second half of the season.

FIRST.com’s top tips – Rams @ Jaguars

Pick 1: Jacksonville Jaguars +3.5 @ 8/11 (William Hill)

Pick 2: Brian Thomas anytime TD scorer @ 11/8 (William Hill)

Pick 3: Over 44.5 points @ 10/11 (Ladbrokes)

Philadelphia Eagles @ Minnesota Vikings betting tips

When: 18:00pm UK time

Where to watch: Sky Sports NFL

The Eagles looked like they had just carried over from last season in the first four weeks as they went 4-0 with little trouble. However, things have changed in the last two weeks with losses to the Denver Broncos and the New York Giants.

There seems to be quite a bit of discontent amongst Eagles fans when it comes to how the offence is being run. Last year Saquon Barkley was featured heavily but that has not been the case under new offensive coordinator Kevin Patullo.

Now the Eagles are going up against another strong defence in the Minnesota Vikings although they have had their own offensive problems. They are currently 3-2 but their quarterback situation is not in great shape. JJ McCarthy looked bad before he got injured and veteran Carson Wentz has his limitations.

After two weeks on the road playing international games, the Vikings had last week off as a bye. This should have helped them rest and recuperate ahead of a big test against the Eagles. 

FIRST.com’s top tips – Eagles @ Vikings

Pick 1: Philadelphia Eagles -1.5 @ 17/20 (William Hill) 

Pick 2: Dallas Goedert anytime TD scorer @ 2/1 (William Hill) 

Pick 3: Under 44.0 points @ 10/11 (Coral)

Indianapolis Colts @ LA Chargers betting tips

When: 21:05pm UK time

Where to watch: Sky Sports NFL

We have got a battle of first place teams here as the LA Chargers, who are first in the AFC West take on the Colts, First in the AFC South. The Indianapolis Colts have been a bit of a surprise package this season as they have a 5-1 record. Only the Rams have beaten them so far.

Daniel Jones has been a revelation since moving to Indianapolis with a 71.7% pass completion rate. Along with rookie tight end Tyler Warren having a great season the Colts look like they could go far into the post-season. Jonathon Taylor has also been in amazing form with 603 rushing yards and seven touchdowns.

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They have got a tough matchup here though as they face the LA Chargers. The Chargers are still managing to produce wins despite having a ton of injury problems. 

Their two main offensive linemen, Rashawn Slater and Joe Alt, are injured. Also, starting running backs Najee Harris and Omarion Hampton won’t suit up either.

Despite this adversity, the Chargers are still winning games and Kimani Vidal showed last week how strong their depth is. He had 124 yards and a touchdown against the Miami Dolphins last week. This should be an exciting watch.

FIRST.com’s top tips Colts @ Chargers

Pick 1: Colts +1.5 @ 20/21 (Betfred) 

Pick 2: Under 48.5 points @ 10/11 (Coral)

Pick 3: Daniel Jones anytime TD scorer @ 13/5 (Betfred)

Washington Commanders @ Dallas Cowboys betting tips

When: 21:25pm UK time

Where: Sky Sports NFL

This matchup has the potential to be an absolute shootout and will most likely be the highest scoring game of the week. 

The Dallas Cowboys have one of the worst defences in the league and can’t stop anyone. They are currently ranked 31st and the least number of points they have given up in a game is 22. That was to the 0-6 New York Jets.

However, their offence is flying now and that will only get better with CeeDee Lamb back from injury. It’s crazy to say that they haven’t missed him, but they truly haven’t. Dak Prescott has passed for 1,617 yards and 13 touchdowns so far in an impressive season so far.

The Washington Commanders have had a bit of a bumpy start to the season and currently have a 3-3 record. They don’t seem to be able to get things going the same way they did last season.

Jayden Daniels has missed a couple of games through injury but was back last week. It felt like he needed to get going again and was much better in the second half of that game. 

The Commanders are still without star wide receiver Terry McLaurin which has been a big loss. There should be plenty of points in this one.

FIRST.com’s top tips -  Commanders @ Cowboys

Pick 1: Dallas Cowboys to win @ 21/20 (Betfred)

Pick 2: Over 54.5 points @ 20/23 (Betfred)

Pick 3: Zack Ertz anytime TD scorer @ 7/4 (Betway)

Atlanta Falcons @ San Francisco 49ers betting tips

When: 01:20am Monday UK time

Where to watch: Sky Sports NFL

The Atlanta Falcons are 3-2 as we go into week seven and are coming off their best result so far this season. Beating the Bills last Monday night was a huge confidence booster. They have had their troubles this year, especially when losing 30-0 against a poor Carolina Panthers team.

Michael Penix who is in his first season as the full-time starting quarterback has shown glimpses of talent but also struggles. 

He has thrown four touchdown passes and three interceptions. Fortunately, star running back Bijan Robinson and receiver Drake London are playing well.

Here they are going up against a San Francisco 49ers team that have been dogged by injuries - but are still 4-2. They have been heavily reliant on Christian McCaffery, but he has proven that his injury worries are behind him for now.

It doesn’t matter if the 49ers start with Brock Purdy or Mac Jones at quarterback, they are still tough to beat. Losing Fred Warner to injury last week is a massive blow however and eventually the pile of injuries will take their toll. Expect this game to be a close one.

FIRST.com’s top tips -  Falcons @ 49ers

Pick 1: San Francisco 49ers -2.0 @ 10/11 (Coral) 

Pick 2: Under 46.5 points @ 1/1 (PricedUp)

Pick 3: Kyle Pitts anytime TD scorer @ 5/2 (Betway) 

Tampa Bay Buccaneers @ Detroit Lions betting tips

When: 00:00 Tuesday UK time

Where to watch: Sky Sports NFL

The Buccaneers have had a great start to the season and sit at the top of the NFC South with a 5-1 record. The only game they lost was to the Eagles. Baker Mayfield has been unbelievable and has put himself in the race for the MVP. He has passed for 1,539 yards, 12 touchdowns and only one interception.

Along with Mayfield being great it has also helped that rookie receiver Emeka Egbuka has had a good start to his NFL career as well. Egbuka has had five touchdowns in six games. 

Unfortunately, he is going to miss this game through injury along with Mike Evans and Chris Godwin.

Despite that the Buccaneers will be competitive against the Lions. The Lions are 4-2 and have looked good despite the changes they had in the offseason. Jared Goff has continued to be reliable at quarterback, and the run game is top notch.

This game should be one of the more exciting ones of the week and is one to stay up for.

FIRST.com’s top tips -  Buccaneers @ Lions

Pick 1: Detroit Lions -5.5 @ 10/11 (Coral)

Pick 2: Over 52.5 points @ 10/11  (PricedUp)

Pick 3: Sam LaPorta anytime TD score @ 33/20 (Betway)

Quickfire predictions – week seven tips

Raiders @ Chiefs

Pick 1: Over 45.5 points @ 10/11

Pick 2: Xavier Worthy anytime TD scorer @ 9/5

Patriots @ Titans

Pick 1: Under 42.0 points @ 10/11

Pick 2: Kayshon Boutte anytime TD scorer @ 23/10

Saints @ Bears

Pick 1: Over 46.5 points @ 10/11

Pick 2: Rome Odunze anytime TD scorer @ 21/20

Dolphins @ Browns

Pick 1: Miami Dolphins +2.5 @ 10/11

Pick 2: Darren Waller anytime TD scorer @ 9/4

Panthers @ Jets

Pick 1: Panthers to win @ 5/6

Pick 2: Rico Dowdle anytime TD scorer @ 11/10

Giants @ Broncos

Pick 1: New York Giants +7.0 @ 10/11

Pick 2: Jaxson Dart anytime TD scorer @ 15/4

Packers @ Cardinals

Pick 1: Over 45.0 points @ 10/11

Pick 2: Trey McBride anytime TD scorer @ 17/10

Texans @ Seahawks

Pick 1: Seattle Seahawks -3.0 @ 10/11

Pick 2: AJ Barner anytime TD scorer @ 3/1

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Odds correct at the time of writing.