Serie A title odds: The pursuit of the Scudetto is heating up nicely

Serie A is arguably one of the most difficult leagues on the continent this season to predict the winner. 

With Manchester City/Liverpool dominating England, Real Madrid and Barcelona sharing La Liga titles of late and Bayern Munich winning all but one of the last 13 Bundesliga titles, the Italian top flight is different.

Indeed, since Juventus won the last of their nine consecutive titles in 2020, three different teams have shared the previous five domestic crowns.

Inter Milan (2021 and 2024), AC Milan (2022) and Napoli (2023 and 2025) have emerged from the Old Lady’s shadow. This season, however, the Serie A race is the most exciting in years.

We at FIRST.com take a look at the latest Serie A outright odds after 11 matchdays of the 2025/26 campaign.

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Inter Milan – 5/6 

Despite suffering a chastening 5-0 defeat to PSG in the Champions League final last season, plus losing manager Simone Inzaghi, Inter remain favourites for a third Serie A title in five years.

After 11 games, Inter have won eight and lost three as they currently sit top of the table on 24 points.

Lautaro Martinez, Hakan Calhanoglu and summer signing Ange-Yoan Bonny have 13 league goals between them this season, suggesting that if they stay fit, the trio could be crucial between now and May.

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Napoli – 4/1

After winning their first Scudetto in 33 years in 2023, Napoli regressed the following campaign, failing to even qualify for Europe as they slipped to tenth.

Step forward Antonio Conte. The Italian had forged a reputation for getting struggling teams back to their best, see Juventus (2011/12), Chelsea (2016/17) and Inter (2020) as perfect examples.

Napoli was no different. Throughout his maiden campaign in charge of the Gli Azzurri, Conte steered the club to another Serie A crown, losing just four matches all season.

Scott McTominay was the hero for the club, netting 12 goals during his maiden season in Serie A, including a goal in their final day win over Cagliari, which sealed the title.

The club currently occupy fourth, although they remain just two points behind Inter after 11 games.

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AC Milan – 9/2

AC Milan might only be third favourites according to Ladbrokes, but without the burden of European football, they might just have the advantage this season.

The Rossoneri finished eighth last term, their worst finish for ten years, which meant the club missed out on qualifying for any of the three European competitions.

Maxi Allegri has since returned as manager. During his first spell between 2010 and 2014, he led Milan to a league title and SuperCoppa Italia glory. Can he replicate his previous success?

So far, Milan have suffered just one defeat and recently defeated fellow title challengers AS Roma 1-0 to sit third, two points behind their city rivals Inter.

Allegri’s men have the third-best attacking record in the top flight. Something which could help propel them to a first domestic crown since 2022.

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AS Roma – 12/1

The last time Roma finished higher than fifth in Serie A was back in 2017/18. That season, they also reached the semi-finals of the Champions League.

This summer, former Atalanta manager Gian Piero Gasperini took over the reigns at the club and looks to finally have them challenging for glory.

Roma have only conceded five goals across their opening 11 league matches – the best defensive record in Serie A.

A 1-0 victory over arch rivals Lazio in matchday four was the highlight, but the capital side have only scored two or more goals in four of their league matches this season.

If Gasperino wishes to lead the club to a first league crown in 25 years, their attacking output will have to improve between now and May.

Juventus – 18/1

Juventus have fallen on hard times in recent years. Without a title since 2020, and only two Coppa Italia trophies, the Old Lady have underperformed of late.

As such, they are fifth favourites to win the league title this season at odds of 18/1. Having sacked Igor Tudor after a poor start to the season, Juventus are on their fourth permanent manager since 2021.

Luciano Spalletti has a wealth of experience, but even he might struggle to get a tune out of this squad, who sit sixth after 11 matches.